Dipropylcarbamoyl chloride → 1-Dipropylcarbamoyl-3-isopropylsulphonyl-1,2,4-triazole

HRID 371582Notes

Reaction equation

[CH:1]([S:4]([C:7]1[N:11]=[CH:10][NH:9][N:8]=1)(=[O:6])=[O:5])([CH3:3])[CH3:2].[CH2:12]([N:15]([CH2:19][CH2:20][CH3:21])[C:16](Cl)=[O:17])[CH2:13][CH3:14]>>[CH2:12]([N:15]([CH2:19][CH2:20][CH3:21])[C:16]([N:9]1[CH:10]=[N:11][C:7]([S:4]([CH:1]([CH3:3])[CH3:2])(=[O:6])=[O:5])=[N:8]1)=[O:17])[CH2:13][CH3:14]

Participants

Reactant 2

HCID 3015348Dipropylcarbamoyl chloride

HCID 178461014HCID 178461014, compound

Product 1

HCID 203550891-Dipropylcarbamoyl-3-isopropylsulphonyl-1,2,4-triazole

Procedure

In an analogous manner to that described in Example 20, 3-isopropylsulphonyl-1,2,4-triazole was reacted with dipropylcarbamoyl chloride (4 hours reflux) to give 1-dipropylcarbamoyl-3-isopropylsulphonyl-1,2,4-triazole, m.p. 61° - 63° C. Elemental analysis satisfactory.

Sources & evidence

ORD record: ord-204e7f23ebfa45be9ce7c8f1bd90b2f8
Source dataset: uspto-grants-1978_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04087269

Reaction notes

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