Phosphorus sulfide (P2S5) → HCID 20355329, compound

HRID 371627Notes

Reaction equation

HRID 371627 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10]3=[CH:12][S:13][CH:14]=[C:9]3[C:8](=O)[NH:7][C:6]=2[CH:16]=1.P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:18]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10]3=[CH:12][S:13][CH:14]=[C:9]3[C:8](=[S:18])[NH:7][C:6]=2[CH:16]=1

Participants

3

Reactant 2

HCID 14817Phosphorus sulfide (P2S5)HCID 12438967HCID 12438967, compound

Product 1

HCID 20355329HCID 20355329, compound

Procedure

In a similar fashion 7-fluoro-4,9-dihydro-10H-thieno[3,4-b][1,5]benzodiazepin-10-one is treated with phosphorus pentasulfide to give 7-fluoro-4,9-dihydro-10H-thieno[3,4-b][1,5]benzodiazepin-10-thione.

Sources & evidence

ORD record
ord-9a35cbbe46a44542868e540cba83e05b
Source dataset
uspto-grants-1978_05
Patent number
US04087421

Reaction notes

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