Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 371665Generated: October 25, 2026

Heptafluorobutyric anhydride → 5-Chloro-3-nitro-2-(heptafluorobutyramido)pyridine

https://huagongshe.com/reaction/371665

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHeptafluorobutyric anhydrideHCID 67643—
Reactant2-Amino-5-chloro-3-nitropyridineHCID 224168—
Product5-Chloro-3-nitro-2-(heptafluorobutyramido)pyridineHCID 20355476—

Reaction Steps

5-Chloro-3-nitro-2-aminopyridine is reacted with heptafluorobutyric anhydride to obtain 5-chloro-3-nitro-2-(heptafluorobutyramido)pyridine which when hydrogenated yields 6-chloro-1-hydroxy-2-(heptafluoro-n-propyl)-1H-imidazo(4,5-b)pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04087432
Source datasetuspto-grants-1978_05
ORD IDord-a93fbdec1b774ef581aaf648d5d9d40d
Source noteuspto-grants-1978_05