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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 37167Generated: October 26, 2026

1-(Bis(4-fluorophenyl)methyl)piperazine → 7-Hydroxy-2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-YL carbonyl}-2,3-dihydro-1,4-benzodioxin

https://huagongshe.com/reaction/37167

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bis(4-fluorophenyl)methyl)piperazineHCID 152932—
Reactant7-Hydroxy-2,3-dihydro-1,4-benzodioxine-2-carboxylic acidHCID 10899551—
Product7-Hydroxy-2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-YL carbonyl}-2,3-dihydro-1,4-benzodioxinHCID 1181264865%

Reaction Steps

That compound is obtained in a yield of 65% starting from 1-[bis(4-fluorophenyl)methyl]piperazine and 7-hydroxy-2,3-dihydro-1,4-benzodioxin-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05420132
Source datasetuspto-grants-1995_05
ORD IDord-e863bd26ea384818ae0a1190e6a5f466
Source noteuspto-grants-1995_05