HRID371672

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2776744

2,2,3,3-tetrafluoropropanoyl chloride

C3HClF4O

结构：Nc1ncc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1[N+](=O)[O-]

HCID20355500

未命名化合物

PRODUCTS

生成物

结构：O=C(Nc1ncc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1[N+](=O)[O-])C(F)(F)C(F)F

HCID20355462

未命名化合物

PROCEDURE

实验过程

5-(Perfluorooctyl)-3-nitro-2-aminopyridine is reacted with 2,2,3,3-tetrafluoropropionyl chloride to obtain 5-(perfluorooctyl)-3-nitro-2-(2,2,3,3-tetrafluoropropionamido)pyridine, which when hydrogenated yields 6-(perfluorooctyl)-1-hydroxy-2-(1,1,2,2-tetrafluoroethyl)-1H-imidazo(4,5-b)pyridine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2bfb6df6f38a4199b20166b7165177f9
来源数据集: uspto-grants-1978_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04087432
来源说明: uspto-grants-1978_05

反应 SMILES

[F:1][C:2]([F:35])([C:25]1[CH:26]=[C:27]([N+:32]([O-:34])=[O:33])[C:28]([NH2:31])=[N:29][CH:30]=1)[C:3]([F:24])([F:23])[C:4]([F:22])([F:21])[C:5]([F:20])([F:19])[C:6]([F:18])([F:17])[C:7]([F:16])([F:15])[C:8]([F:14])([F:13])[C:9]([F:12])([F:11])[F:10].[F:36][C:37]([F:44])([CH:41]([F:43])[F:42])[C:38](Cl)=[O:39]>>[F:35][C:2]([F:1])([C:25]1[CH:26]=[C:27]([N+:32]([O-:34])=[O:33])[C:28]([NH:31][C:38](=[O:39])[C:37]([F:44])([F:36])[CH:41]([F:43])[F:42])=[N:29][CH:30]=1)[C:3]([F:23])([F:24])[C:4]([F:21])([F:22])[C:5]([F:19])([F:20])[C:6]([F:18])([F:17])[C:7]([F:16])([F:15])[C:8]([F:14])([F:13])[C:9]([F:12])([F:11])[F:10]