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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 37171Generated: October 30, 2026

1-(Bis(4-fluorophenyl)methyl)piperazine → 6-Hydroxy-7-tert-butyl-2-{4-[bis-(4-fluorophenyl) methyl]piperazin-1-ylcarbonyl}-1,4-benzodioxin

https://huagongshe.com/reaction/37171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bis(4-fluorophenyl)methyl)piperazineHCID 152932—
Reactant6-Hydroxy-7-tert-butyl-1,4-benzodioxin-2-carboxylic acidHCID 11086169—
Product6-Hydroxy-7-tert-butyl-2-{4-[bis-(4-fluorophenyl) methyl]piperazin-1-ylcarbonyl}-1,4-benzodioxinHCID 1104960883%

Reaction Steps

That compound is obtained in a yield of 83% starting from 1-[bis-(4-fluorophenyl)methyl]piperazine and 6-hydroxy-7-tert-butyl-1,4-benzodioxin-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05420132
Source datasetuspto-grants-1995_05
ORD IDord-9af6ddd1236f457d8789cf236e6599cd
Source noteuspto-grants-1995_05