Sodium Hydroxide → HCID 23713915, compound

HRID 371744Notes

Reaction equation

HRID 371744 reaction equation
[C:1]1([C:6]([C:8]2[N:12]3[CH2:13][CH2:14][CH:15]([C:16]([OH:18])=[O:17])[C:11]3=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+:20]>CO>[C:1]1([C:6]([C:8]2[N:12]3[CH2:13][CH2:14][CH:15]([C:16]([O-:18])=[O:17])[C:11]3=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1.[Na+:20]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 20356074HCID 20356074, compound

Product 1

HCID 23713915HCID 23713915, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 300 mg. of 5-(2-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid in 5 ml. of methanol is added 1 molar equivalent of sodium hydroxide, in the form of a 0.1N solution. The solvent is then evaporated under reduced pressure and the residue taken up in 2 ml. of methanol, followed by precipitation with ether, to yield crude sodium 5-(2-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate which can be crystallized from isopropanol.

Workup

  1. customThe solvent is then evaporated under reduced pressure
  2. customof methanol, followed by precipitation with ether

Sources & evidence

ORD record
ord-9c29696d9f1c4f589a3711b4442b212b
Source dataset
uspto-grants-1978_05
Patent number
US04087539

Reaction notes

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