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HRID371752

反应详情

EQUATION

反应方程式

HRID 371752 的结构方程式

REACTANTS

反应物

1
结构：C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c4c(c3)O[C@H](c3ccc(O)cc3)CC4=O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
HCID442428

Naringin

C27H32O14

PRODUCTS

生成物

2
结构：C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c4c(c3)O[C@H](c3ccc(O)cc3)CC4=O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
HCID442428

Naringin

C27H32O14

结构：C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c(C(=O)CCc4ccc(O)cc4)c(O)c3)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
HCID9894584

Naringin dihydrochalcone

C27H34O14

AUXILIARIES

试剂、催化剂与溶剂

3
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：O
溶剂HCID962

Water

H2O

结构：[K+].[OH-]
溶剂HCID14797

Potassium hydroxide

HKO

PROCEDURE

实验过程

Five grams of naringin are dissolved in 25 ml of a 10% aqueous solution of potassium hydroxide and hydrogenated at room temperature and at atmospheric pressure, using 500 mg palladium black as catalyst. The resultant colorless solution is diluted with water; after removal of the catalyst the solution is passed through an Amberlite 200 (Rohm & Haas) column, and the alkaline-free eluate is evaporated to dryness. White crystals of the dihydrochalcone of naringin are obtained, m.p. 169°-170° C, in a yield of 98%.

WORKUP

后处理

  1. customafter removal of the catalyst the solution
  2. customthe alkaline-free eluate is evaporated to dryness