HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxyquinoline → Quinoline, 1,2,3,4-tetrahydro-6-methoxy-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxyquinoline | HCID 14860 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Quinoline, 1,2,3,4-tetrahydro-6-methoxy- | HCID 67113 | 94.6% |
Reaction Steps
6-Methoxyquinoline (1.00g) was dissolved in absolute ethanol (20 ml) and hydrogenated under pressure in the presence of 10% palladium on charcoal (0.10g) with shaking for about 40 hours. Filtration and evaporation to dryness of the filtrate gave 1,2,3,4-tetrahydro-6-methoxyquinoline as a light-brown gum (0.97g). The structure was supported by nmr spectrum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04087561 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-1d27416b936e4f4b9c7fc294a512a2d7 |
| Source note | uspto-grants-1978_05 |