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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 37177Generated: October 25, 2026

Trimetazidine → 7-Hydroxy-2-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylcarbonyl]-1,4-benzodioxin

https://huagongshe.com/reaction/37177

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimetazidineHCID 21109—
Reactant7-Hydroxy-1,4-benzodioxin-2-carboxylic acidHCID 10932311—
Product7-Hydroxy-2-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylcarbonyl]-1,4-benzodioxinHCID 1097225273%

Reaction Steps

That compound is obtained in a yield of 73% starting from 1-(2,3,4-trimethoxybenzyl)piperazine and 7-hydroxy-1,4-benzodioxin-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05420132
Source datasetuspto-grants-1995_05
ORD IDord-88a804730c8f403b9a86619d14d18910
Source noteuspto-grants-1995_05