HuagongsheHuagongshe Chemistry Print Report · For research reference only
19-Hydroxy-1beta-methyl-4-androsten-3,17-dione → 1beta-Methyl-19-triphenylsiloxy-4-androstene-3,17-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 19-Hydroxy-1beta-methyl-4-androsten-3,17-dione | HCID 54279369 | — |
| Reactant | 19-Hydroxy-6alpha-methyl-4-androstene-3,17-dione | HCID 70583925 | — |
| Reactant | 19-(Triphenylsiloxy)-4-androstene-3,17-dione methanolate | HCID 86735679 | — |
| Product | 1beta-Methyl-19-triphenylsiloxy-4-androstene-3,17-dione | HCID 22803265 | — |
| Product | 6alpha-Methyl-19-triphenylsiloxy-4-androstene-3,17-dione | HCID 22803273 | — |
Reaction Steps
Following essentially the same procedure but substituting 19-hydroxy-1β-methyl-4-androstene-3,17-dione and 19-hydroxy-6α-methyl-4-androstene-3,17-dione for the 19-hydroxy-4-androstene-3,17-dione above results in the preparation of 1β-methyl-19-triphenylsiloxy-4-androstene-3,17-dione and 6α-methyl-19-triphenylsiloxy-4-androstene-3,17-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04087524 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-b4c906bcf4c147b3900b530dee47499a |
| Source note | uspto-grants-1978_05 |