HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 1alpha-Methyl-4-androstene-3beta,17beta,19-triol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 17beta,19-Dihydroxy-1alphamethyl-4-androsten-3-one | HCID 22797425 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1alpha-Methyl-4-androstene-3beta,17beta,19-triol | HCID 70586374 | — |
Reaction Steps
17β,19-Dihydroxy-1α-methyl-4-androsten-3-one is dissolved in ethanol and sodium borohydride is added slowly under nitrogen. After stirring at room temperature for 4 hours, the solution is poured onto ice water containing a few drops of acetic acid. The solid which forms is filtered and recrystallized from ethanol to yield 1α-methyl-4-androstene-3β,17β,19-triol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04087524 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-3d99a8c8175645548a45cc069f250fe7 |
| Source note | uspto-grants-1978_05 |