Acetic Anhydride → HCID 20319174, compound

HRID 371865Notes

Reaction equation

HRID 371865 reaction equation
[ClH:1].[NH2:2][C:3]1[C:14]([Br:15])=[CH:13][C:12]([CH3:16])=[CH:11][C:4]=1[CH2:5][N:6]([CH2:9][CH3:10])[CH2:7][CH3:8].[C:17](OC(=O)C)(=[O:19])[CH3:18]>>[ClH:1].[NH:2]([C:3]1[C:14]([Br:15])=[CH:13][C:12]([CH3:16])=[CH:11][C:4]=1[CH2:5][N:6]([CH2:9][CH3:10])[CH2:7][CH3:8])[C:17]([CH3:18])=[O:19]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 20318970HCID 20318970, compound

Product 1

HCID 20319174HCID 20319174, compound

Procedure

1.53 gm of 2-amino-3-bromo-N,N-diethyl-5-methyl-benzylamine hydrochloride were dissolved in 50 ml of acetic acid anhydride at 75° C. The solution was evaporated to dryness in vacuo, and the residue was recrystallized from ethanol, yielding 2-acetamino-3-bromo-N,N-diethyl-5-methyl-benzylamine hydrochloride, m.p. 170-172° C.

Workup

  1. customThe solution was evaporated to dryness in vacuo
  2. customthe residue was recrystallized from ethanol

Sources & evidence

ORD record
ord-073a7be9b4b341e998f188cbded772c2
Source dataset
uspto-grants-1978_05
Patent number
USRE029628

Reaction notes

Loading…