N-Methylcyclohexylamine → HCID 54118647, compound

HRID 371879Notes

Reaction equation

HRID 371879 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([O:10][CH3:11])=[CH:6][C:3]=1[CH2:4]O.S(Cl)(Cl)=O.[CH3:16][NH:17][CH:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>C(Cl)Cl>[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([O:10][CH3:11])=[CH:6][C:3]=1[CH2:4][N:17]([CH:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1)[CH3:16]

Participants

5

Reactant 3

HCID 7514N-MethylcyclohexylamineHCID 24386Thionyl ChlorideHCID 13756678(2-Amino-5-methoxyphenyl)methanol

Product 1

HCID 54118647HCID 54118647, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-Amino-N-cyclohexyl-5-methoxy-N-methyl-benzylamine was prepared from 2-amino-5-methoxy-benzyl alcohol, thionyl chloride and N-methyl-cyclohexylamine analogous to Example 1. Proof of structure by IR- and UV-spectra. IR-spectrum (methylenechloride): 3240 cm-1NH2 ; 3400 cm-1NH2 ; 2780 cm-1N-methyl; 2830 cm-1OCH3 ; 2850 cm-1 aliphatic hydrocarbon; 2930 cm-1 aliphatic hydrocarbon; 1500 cm-1C=C; 1510 cm-1C=C.

Sources & evidence

ORD record
ord-b0d2aeb44655424ba2ee1fcccc7529bb
Source dataset
uspto-grants-1978_05
Patent number
USRE029628

Reaction notes

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