Sodium borohydride → HCID 20319225, compound

HRID 371884Notes

Reaction equation

[C:1]([C:4]1[CH:5]=[C:6]([Br:15])[C:7]([NH2:14])=[C:8]([CH:13]=1)[CH2:9][N:10]([CH3:12])[CH3:11])(=[O:3])[CH3:2].[BH4-].[Na+]>>[NH2:14][C:7]1[C:6]([Br:15])=[CH:5][C:4]([CH:1]([OH:3])[CH3:2])=[CH:13][C:8]=1[CH2:9][N:10]([CH3:12])[CH3:11]

Participants

Reactant 2

HCID 4311764Sodium borohydride

HCID 20319170HCID 20319170, compound

Product 1

HCID 20319225HCID 20319225, compound

Procedure

2-Amino-3-bromo-N,N-dimethyl-5-(1-hydroxy-ethyl)-benzylamine, m.p. 69-72° C was prepared by reduction of 5-acetyl-2-amino-3-bromo-N,N-dimethyl-benzylamine with sodium borohydride analogous to Example 19.

Sources & evidence

ORD record: ord-48ffcd0dfc04461d891b3e714092faf3
Source dataset: uspto-grants-1978_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: USRE029628

Reaction notes

Loading…