4-Fluoroaniline → N-(4-fluorophenyl)-2-[[2-[(4-fluorophenyl)carbamoyl]phenyl]disulfanyl]benzamide

Participants

Reaction Steps

This compound was prepared according to the general method of Example 77 using 2,2'-dithiobisbenzoyl chloride (1.00 g, 2.92 mmol) in 20 mL of dichloromethane and 4-fluoroaniline (0.657 g, 5.91 mmol) in 5 mL of pyridine. The crude product was triturated with hot ethanol-ethyl acetate mixture, filtered, and recrystallized from ethanol-DMF to yield 0.14 g of the title compound, mp 242°-244° C.

Provenance & Evidence