HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-chloro-3-ethyl-5-methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid, ethyl ester → 3,5-dimethyl-7-ethoxy-3H-imidazo-[4,5-b]pyridine-6-carboxylic acid, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-chloro-3-ethyl-5-methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid, ethyl ester | HCID 12387638 | — |
| Reactant | 7-chloro-3,5-dimethyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid ethyl ester | HCID 12387640 | — |
| Product | 3,5-dimethyl-7-ethoxy-3H-imidazo-[4,5-b]pyridine-6-carboxylic acid, ethyl ester | HCID 54295511 | 78% |
Reaction Steps
By replacing 7-chloro-3-ethyl-5-methyl-3H-imidazo-[4,5-b]pyridine-6-carboxylic acid, ethyl ester in Example 1 e with 7-chloro-3,5-dimethyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid ethyl ester, 3,5-dimethyl-7-ethoxy-3H-imidazo[4,5-b]pyridine -6-carboxylic acid, ethyl ester is obtained. Yield 78%, m.p. 85°-87° (ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04088654 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-70963b22e0464f169bdcdea1396fe8c8 |
| Source note | uspto-grants-1978_05 |