HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 20468400, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Reactant | 1-Phenyl-3-azabicyclo[3.1.0]hexane | HCID 10130094 | — |
| Solvent | Benzene | HCID 241 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20468400 | HCID 20468400 | — |
Reaction Steps
A 6.4 g. portion of 1-phenyl-3-azabicyclo[3.1.0]-hexane is added to 60 ml. of benzene. A 4.2 g. portion of sodium carbonate in 40 ml. of water is added with stirring. A 6.3 g. portion of p-fluorobenzoyl chloride in 40 ml. of benzene is added and the mixture is stirred overnight. The solid in the aqueous layer is recovered by filtration, washed with water and slurried in ether giving the product as white crystals, mp 101°-103° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04088652 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-e7e0d01a72db4704b71bf1feb9372dbb |
| Source note | uspto-grants-1978_05 |