HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 3-(1-Adamantylcarbonyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-Adamantanecarbonyl chloride | HCID 98915 | — |
| Reactant | 1-(4-Chlorophenyl)-3-azabicyclo[3.1.0]hexane | HCID 10130331 | — |
| Product | 3-(1-Adamantylcarbonyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane | HCID 20468354 | — |
Reaction Steps
Following the procedure of Example 8, 19.35 g. of 1-p-chlorophenyl-3-azabicyclo[3.1.0]hexane, 10.59 g. of sodium carbonate and 19.87 g. of 1-adamantanecarboxylic acid chloride are reacted, yielding the product as a white solid, mp 163°-165° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04088652 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-30d6be06161c4fa991b9b4843d7fb6c6 |
| Source note | uspto-grants-1978_05 |