HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Acetyl-1-(p-nitrophenyl)-3-azabicyclo[3.1.0]hexane → 3-Acetyl-1-(p-aminophenyl)-3-azabicyclo[3.1.0]hexane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Acetyl-1-(p-nitrophenyl)-3-azabicyclo[3.1.0]hexane | HCID 20352253 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Acetyl-1-(p-aminophenyl)-3-azabicyclo[3.1.0]hexane | HCID 20468332 | — |
Reaction Steps
A solution of 3-acetyl-1-(p-nitrophenyl)-3-azabicyclo[3.1.0]hexane in tetrahydrofuran is hydrogenated at atmospheric pressure and ambient temperature using a 5% palladium on charcoal catalyst. Filtration and evaporation of the filtrate under reduced pressure gives 3-acetyl-1-(p-aminophenyl)-3-azabicyclo[3.1.0]hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04088652 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-a6e2eb97d6524f8eac2d72f63e0b7ff3 |
| Source note | uspto-grants-1978_05 |