HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1-Methylcarbamoyl-4-(3',5'-dichlorophenyl) urazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 4-(3,5-Dichlorophenyl)-1,2,4-triazolidine-3,5-dione | HCID 18755009 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-Methylcarbamoyl-4-(3',5'-dichlorophenyl) urazole | HCID 53634534 | — |
Reaction Steps
To a solution of 2.5 g of 4-(3',5'-dichlorophenyl) urazole in 10 ml of N,N-dimethylformamide were added a drop of triethylamine and, in turn, 0.8 g of methyl isocyanate dropwise at room temperature with agitation. The reaction was continued for one additional hour under the same conditions and the reaction mixture was poured in water to precipitate crystals which were filtered and recrystallized from acetoneethanol to obtain 1-methylcarbamoyl-4-(3',5'-dichlorophenyl) urazole in an amount of 2.1 g (yield being 68%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04088767 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-7e08e28a5ddb45e792dc145ae6ac7e1e |
| Source note | uspto-grants-1978_05 |