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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 37206Generated: October 29, 2026

Acetic Acid → 4-[(2-Butyl pyrazolo(1,5-a) pyridin-3-yl) carbonyl]benzoic acid

https://huagongshe.com/reaction/37206

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantSulfuric AcidHCID 1118—
Reactant(2-Butylpyrazolo(1,5-a)pyridin-3-yl)carbonyl benzonitrileHCID 86748690—
SolventWaterHCID 962—
Product4-[(2-Butyl pyrazolo(1,5-a) pyridin-3-yl) carbonyl]benzoic acidHCID 21472332—

Reaction Steps

A mixture of 845 mg of the product of Example 2 and 15 ml of a mixture in equal proportions of sulfuric acid, acetic acid and water was refluxed for 2 hours and the mixture was cooled down, taken up in water, filtered, washed with water and dried at 80° C. under reduced pressure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05420138
Source datasetuspto-grants-1995_05
ORD IDord-61b16523a7764a7a8d917dd5cae5cf31
Source noteuspto-grants-1995_05