1,1-Dimethylethyl 4'-[(2-butyl pyrazolo (1,5-a)pyridin-3-yl)methyl]-(1,1-biphenyl) 2-carboxylate → 1,1-Dimethylethyl 4'-[(2-butyl 4,5,6,7-tetrahydro pyrazolo(1,5-a)pyridin-3-yl)methyl](1,1'-biphenyl)2-carboxylate

Participants

Reaction Steps

220 g of the product of Example 6, 20 ml of acetic acid and 100 mg of 82% platinum dioxide. Filtration was carried out followed by extraction with ethyl acetate. The extracts were purified by chromatography on silica (essence G: 80/ethyl acetate: 20) to obtain 145 mg of the expected product.

Provenance & Evidence