HCID 70619502, compound → HCID 13136234, compound

HRID 372154Notes

Reaction equation

HRID 372154 reaction equation
[CH2:1]([C:3]1([CH2:26][CH2:27][C:28]([O:30][CH3:31])=[O:29])[CH:12]2[N:7]([CH2:8][CH2:9][C:10]3[C:19]4[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=4)[NH:13][C:11]=32)[CH2:6][CH2:5][CH:4]1CCC(OC)=O)[CH3:2]>[Pd].CO>[CH2:1]([C:3]1([CH2:26][CH2:27][C:28]([O:30][CH3:31])=[O:29])[CH:12]2[N:7]([CH2:8][CH2:9][C:10]3[C:19]4[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=4)[NH:13][C:11]=32)[CH2:6][CH2:5][CH2:4]1)[CH3:2]

Participants

4

Reactant 1

HCID 70619502HCID 70619502, compound

Product 1

HCID 13136234HCID 13136234, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

An isomer mixture of a ratio described in Example 2 is obtained when dissolving 147 g. of 1-ethyl-(methoxycarbonylethyl)--(methoxycarbonylethyl)-1,2,3,4,6,7-hexahydro-12H-indolo[2,3-a]quinolizine in 16 ml. of methanol and hydrogenating in the presence of 100 mg. palladium on charcoal catalyst.

Workup

  1. additionAn isomer mixture of a ratio
  2. customis obtained when
  3. dissolutiondissolving 147 g

Sources & evidence

ORD record
ord-909007af3207456a913cfbadf84a299a
Source dataset
uspto-grants-1978_05
Patent number
US04089856

Reaction notes

Loading…