HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Cresol → 1-Methyl[cyclohexyl]-3-cyclohexyl[methyl]-5-(methoxy-carbonyl-methylene)-hydantoin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Cresol | HCID 335 | — |
| Reactant | 1-Cyclohexyl-3-methylurea | HCID 308344 | — |
| Reactant | 1-Cyclohexyl-3-methylimidazolidine-2,4-dione | HCID 1521461 | — |
| Reactant | Dimethyl maleate | HCID 5271565 | — |
| Reactant | 3-Cyclohexyl-1-methylimidazolidine-2,4-dione | HCID 16093102 | — |
| Product | 1-Methyl[cyclohexyl]-3-cyclohexyl[methyl]-5-(methoxy-carbonyl-methylene)-hydantoin | HCID 70627789 | — |
Reaction Steps
78 g of N-methyl-N'-cyclohexyl urea, 220 g of cresol and 72 g of dimethyl maleate were stirred at 185° C for one hour and then at 200° C for one hour. 15 g of methanol distilled over during this time. After fractional distillation, a main fraction boiling at 180°-185° C/0.08 Torr could be isolated. It consisted of an isomeric mixture of 1-methyl-3-cyclohexyl-hydantoin and 1-cyclohexyl-3-methylhydantoin but its exact composition could not be determined by gas chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04089860 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-71f239a28a5e4e13ac7d6c3ae3967c0a |
| Source note | uspto-grants-1978_05 |