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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 372227Generated: October 27, 2026

4,N,N-Trimethylbenzamide → isopropyl 5-p-toluoyl-1,2-dihydro-6-methyl-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate

https://huagongshe.com/reaction/372227

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,N,N-TrimethylbenzamideHCID 84179—
Reactantisopropyl 1,2-dihydro-6-methyl-3H-pyrrolo[1,2-a]pyrrole-1-carboxylateHCID 12795099—
Productisopropyl 5-p-toluoyl-1,2-dihydro-6-methyl-3H-pyrrolo[1,2-a]pyrrole-1-carboxylateHCID 13780958—

Reaction Steps

In accordance with the method of Example 8, isopropyl 1,2-dihydro-6-methyl-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate is condensed with N,N-dimethyl-p-toluamide, to produce isopropyl-5-p-toluoyl-1,2-dihydro-6-methyl-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate (XI, R = CH3, R1 = p-CH3, R2 = iC3H7).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04089969
Source datasetuspto-grants-1978_05
ORD IDord-77d3fde4932c4133b34d4240e81c3161
Source noteuspto-grants-1978_05