Acetic Anhydride → 1,2,3,4-Tetrahydro-4-acetoxy-1-naphthylurea

HRID 372282Notes

Reaction equation

HRID 372282 reaction equation
[C:1]([O:4][C:5](=[O:7])[CH3:6])(=O)[CH3:2].OC1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]([NH:19][C:20]([NH2:22])=[O:21])[CH2:11]C1>O>[C:5]([O:4][CH:1]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]([NH:19][C:20]([NH2:22])=[O:21])[CH2:11][CH2:2]1)(=[O:7])[CH3:6]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 42945181,2,3,4-Tetrahydro-4-hydroxy-1-naphthylurea

Product 1

HCID 203516861,2,3,4-Tetrahydro-4-acetoxy-1-naphthylurea

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 10 ml of acetic anhydride 2.0 g of 1,2,3,4-tetrahydro-4-hydroxy-1-naphthylurea (cis/trans) is added and the mixture stirred for 1 hour. The mixture is poured into water and the title compound collected by filtration. Evaporation of the mother liquor in vacuo affords additional title compound.

Workup

  1. filtrationthe title compound collected by filtration
  2. customEvaporation of the mother liquor in vacuo

Sources & evidence

ORD record
ord-270246bffdbe4dbcb0c77ca9061c1b8d
Source dataset
uspto-grants-1978_05
Patent number
US04089976

Reaction notes

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