HCID 12803438, compound → HCID 13093657, compound

HRID 372294Notes

Reaction equation

HRID 372294 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:7]([C:16](=[O:18])[CH3:17])[C:6]1=[O:19].[H][H]>[Pd].C(O)C>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:9][CH:8]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:7]([C:16](=[O:18])[CH3:17])[C:6]1=[O:19]

Participants

5

Reactant 2

HCID 12803438HCID 12803438, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 13093657HCID 13093657, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Approximately 3.9 g. of 1-(2-methoxyethyl)-3-acetyl-4-phenyl-4-imidazolin-2-one and 400 mg. of 10% palladium on carbon in 30 ml. of ethanol is hydrogenated in the Parr Shaker apparatus at 30 psig of hydrogen. After one hour the catalyst is filtered and washed with 50 ml. of ethanol. The combined filtrate is concentrated to yield the title compounds as a colorless oil.

Workup

  1. filtrationAfter one hour the catalyst is filtered
  2. washwashed with 50 ml
  3. concentrationThe combined filtrate is concentrated

Sources & evidence

ORD record
ord-a6814553d39e4a479f4c5ef37a8e10ed
Source dataset
uspto-grants-1978_05
Patent number
US04090025

Reaction notes

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