HCID 178419078, compound → HCID 178513912, compound

HRID 372385Notes

Reaction equation

HRID 372385 reaction equation
[NH2:1][C@H](C(O)=O)CC1N=CNC=1.C([S:15][CH2:16][CH:17]([CH2:32][C:33]([O:35]C)=O)[C:18]([NH:20][C@H:21]([C:29]([OH:31])=[O:30])[CH2:22][CH2:23][CH2:24][NH:25][C:26](=N)[NH2:27])=[O:19])(=O)C>>[SH:15][CH2:16][CH:17]([CH2:32][C:33](=[O:35])[NH2:1])[C:18]([NH:20][C@H:21]([C:29]([OH:31])=[O:30])[CH2:22][C:23]1[N:27]=[CH:26][NH:25][CH:24]=1)=[O:19]

Participants

3

Reactant 2

HCID 178419078HCID 178419078, compoundHCID 178500599HCID 178500599, compound

Product 1

HCID 178513912HCID 178513912, compound

Procedure

By substituting Nα -[3-(acetylthio)-2-methoxycarbonylmethyl)propanoyl]-L-histidine for the Nα -[3-(acetylthio)-2-(methoxycarbonylmethyl)propanoyl]-L-arginine in the procedure of Example 19, Nα -[3-mercapto-2-(carbamoylmethyl)propanoyl]-L-histidine is obtained.

Sources & evidence

ORD record
ord-b761d79aea3843f7b8c658b8187e5c18
Source dataset
uspto-grants-1978_05
Patent number
US04091024

Reaction notes

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