Potassium cyanate → Urea, (1,2,3,4-tetrahydro-4-oxo-1-naphthalenyl)-

HRID 372396Notes

Reaction equation

HRID 372396 reaction equation
Cl.[O:2]=[C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]([NH2:13])[CH2:5][CH2:4]1.[O-:14][C:15]#[N:16].[K+]>O>[O:2]=[C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]([NH:13][C:15]([NH2:16])=[O:14])[CH2:5][CH2:4]1

Participants

4

Reactant 2

HCID 11378442Potassium cyanateHCID 203273204-Amino-1,2,3,4-tetrahydronaphthalen-1-one hydrochloride

Product 1

HCID 3628438Urea, (1,2,3,4-tetrahydro-4-oxo-1-naphthalenyl)-

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A sample of 26.55 g. of 1,2,3,4-tetrahydro-4-oxo-1-naphthylamine hydrochloride is dissolved in 250 ml. water and a solution of 21.8 g. of potassium cyanate in 75 ml. of water added. The reaction mixture is stirred for 72 hours, the precipitate formed in the reaction is collected by filtration and dried to afford 21.45 g. of the title compound, m.p. 225° C. (dec.).

Workup

  1. customthe precipitate formed in the reaction
  2. filtrationis collected by filtration
  3. customdried
  4. customto afford 21.45 g

Sources & evidence

ORD record
ord-b05a0acf721946db8352cf46d448da4b
Source dataset
uspto-grants-1978_05
Patent number
US04091018

Reaction notes

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