HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 7-(methanesulfonamido)heptanoate → 7-[N-(4(R)-hydroxy-2-nonynyl)methanesulfonamido]heptanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 7-(methanesulfonamido)heptanoate | HCID 12150839 | — |
| Reactant | Ethyl 7-(propanesulfonamido)heptanoate | HCID 20327664 | — |
| Reactant | ethyl 7-[N-(4-acetoxynonyl)propanesulfonamido]heptanoate | HCID 20327689 | — |
| Product | 7-[N-(4(R)-hydroxy-2-nonynyl)methanesulfonamido]heptanoic acid | HCID 22798404 | — |
Reaction Steps
The synthesis of this compound is carried out as described in Example 1 except that, in Step A, the ethyl 7-(methanesulfonamido)heptanoate is replaced by an equimolar amount of ethyl 7-(propanesulfonamido)heptanoate (Example Q). The product of Step A is thus ethyl 7-[N-(4-acetoxynonyl)propanesulfonamido]heptanoate. The subsequent hydrolysis step yields 7-[N-(4-hydroxynonyl)propanesulfonamido]heptanoic acid (B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04091107 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-986f3089cfae4a7c923e27fb2fbe5dd5 |
| Source note | uspto-grants-1978_05 |