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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 372571Generated: October 30, 2026

Maleic Anhydride → 3-(4-Chlorobenzoyl)-acrylic acid

https://huagongshe.com/reaction/372571

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMaleic AnhydrideHCID 7923—
ReactantChlorobenzeneHCID 7964—
Product3-(4-Chlorobenzoyl)-acrylic acidHCID 34643—

Reaction Steps

3-(4-chlorobenzoyl)acrylic acid (1A) was prepared, as a yellow crystalline solid, m.p.: 157°-158° C, by the Friedel-Crafts acylation of chlorobenzene with maleic anhydride by the method of Papa et al., J. Am. Chem. Soc., 70, 3356 (1948).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04091221
Source datasetuspto-grants-1978_05
ORD IDord-025f6b12e820412eb8785b425db3a963
Source noteuspto-grants-1978_05