Phosphorus sulfide (P2S5) → HCID 178454407, compound

HRID 372593Notes

Reaction equation

[CH2:1]([O:5][N:6]1[CH:13]=[C:12]([CH3:14])[C:10](=O)[NH:9][C:7]1=[O:8])[CH2:2][CH2:3][CH3:4].C(ONC(N)=O)CCC.P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:25]>>[CH2:1]([O:5][N:6]1[CH:13]=[C:12]([CH3:14])[C:10]([SH:25])=[N:9][C:7]1=[O:8])[CH2:2][CH2:3][CH3:4]

Participants

Reactant 3

HCID 14817Phosphorus sulfide (P2S5)

HCID 313318butoxyurea

HCID 20526200HCID 20526200, compound

Product 1

HCID 178454407HCID 178454407, compound

Procedure

In a manner analogous to that described in Example 1 25 g of 1-butoxy-5-methyl-uracil prepared by reacting of butoxyurea with β,β,-diethoxy-α-methylpropionic acid ester was reacted with 50 g of phosphorus pentasulfide to give 1-butoxy-1,2-dihydro-4-mercapto-5-methyl-2-oxo-pyrimidine;

Workup

customprepared

Sources & evidence

ORD record: ord-851bae66132540eda51ce26a891472c1
Source dataset: uspto-grants-1978_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04091211

Reaction notes

Loading…