HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 6-Amino-4-chloro-2-isopropylamino-5-pyrimidinecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 4,6-Dichloro-2-ethylamino-5-pyrimidinecarbonitrile | HCID 20510256 | — |
| Product | 6-Amino-4-chloro-2-isopropylamino-5-pyrimidinecarbonitrile | HCID 20510226 | — |
Reaction Steps
This compound was prepared in the manner of Example XVII, substituting 4,6-dichloro-2-isopropylamino-5-pyrimidinecarbonitrile and aqueous ammonia for 4,6-dichloro-2-ethylamino-5-pyrimidinecarbonitrile and isopropylamine. The reaction product was recrystallized from benzene to give 6-amino-4-chloro-2-isopropylamino-5-pyrimidinecarbonitrile; mp, 162°-165°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04092150 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-fe8094ed5f3c4599b94061ea24c0af93 |
| Source note | uspto-grants-1978_05 |