反应详情

A mixture of 0.40 g. of 6-(p-cyanophenyl)-3-chloropyridazine and 0.70 g. of 97% ethyl carbazate in 25 ml. of n-butanol is prepared. The solution is stirred and heated at reflux temperature for 4 hours. The reaction mixture is cooled to room temperature and the product precipitated from solution. The product is filtered, washed with n-butanol, water, dried and recrystallized from ethanol giving a crystalline material, m.p. 235° C.

1. additionA mixture of 0.40 g
2. temperatureheated
3. temperatureat reflux temperature for 4 hours
4. customthe product precipitated from solution
5. filtrationThe product is filtered
6. washwashed with n-butanol, water
7. customdried
8. customrecrystallized from ethanol giving a crystalline material, m.p. 235° C.