反应详情

A mixture of 5.0 g. of 6-(p-chlorophenyl)-3-chloropyridazine and 6.86 g. of ethyl carbazate in 80 ml. of n-butyl alcohol is prepared. This solution is stirred and heated at reflux temperature for 4 hours. The reaction mixture is cooled in an ice bath and the resulting solid filtered, washed with n-butyl alcohol, water and dried. The product is recrystallized from ethanol to give crystalline material, m.p. 190°-192° C.

1. additionA mixture of 5.0 g
2. temperatureheated
3. temperatureat reflux temperature for 4 hours
4. temperatureThe reaction mixture is cooled in an ice bath
5. filtrationthe resulting solid filtered
6. washwashed with n-butyl alcohol, water
7. customdried
8. customThe product is recrystallized from ethanol
9. customto give crystalline material, m.p. 190°-192° C.