Ammonium Hydroxide → Ethyl 3-(5-methyl-6-phenyl-3-pyridazinyl)carbazate

Participants

Reaction Steps

A 4.0 g. portion of ethyl 3-[6-(p-bromophenyl)-5-methyl-3-pyridazinyl]carbazate and 0.9 g. of 10% palladium on carbon catalyst in 100 ml. of ethanol and 50 ml. of ammonium hydroxide is shaken under 40 lb. of hydrogen pressure for 4 hours with external heating of the bottle by means of a heated jacket. The reaction mixture is suction filtered and the filtrate is concentrated to a light yellow oil which is scratched with petroleum ether to give a white solid, m.p. 142°-145° C.

Provenance & Evidence