HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazinecarboxylic acid, ethyl ester → Ethyl 3-[6-(p-fluorophenyl)-3-pyridazinyl]carbazate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazinecarboxylic acid, ethyl ester | HCID 20064 | — |
| Reactant | 3-chloro-6-(4-fluorophenyl)pyridazine | HCID 6422444 | — |
| Reactant | 3-[6-(p-Fluorophenyl)-3-pyridazinyl]carbazate | HCID 20326538 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | Ethyl 3-[6-(p-fluorophenyl)-3-pyridazinyl]carbazate | HCID 20326485 | — |
Reaction Steps
A mixture of 5.0 g. of 6-(p-fluorophenyl)-3-chloropyridazine, 5.0 g. of ethyl carbazate and 50 ml. of n-butanol is refluxed for 2 hours. The solvent is removed and the residue washed with water and recrystallized from ethanol to give 1.75 g. of 3-[6-(p-fluorophenyl)-3-pyridazinyl]carbazate as crystals, m.p. 173°-174° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04092311 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-d3e082294ca846b194f0823b893fdadb |
| Source note | uspto-grants-1978_05 |