HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11673142, compound → HCID 53790063, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11673142 | HCID 11673142 | — |
| Reactant | L-Tryptophan, N-[(1,1-dimethylethoxy)carbonyl]-, 2,4,5-trichlorophenyl ester | HCID 22788750 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 53790063 | HCID 53790063 | — |
Reaction Steps
A solution of 26.6 parts N-t-butoxycarbonyl-L-tryptophan 2,4,5-trichlorophenyl ester and 12.0 parts L-methionine benzyl ester in 200 parts methylene chloride is stirred overnight at room temperature. The solvent is then removed by evaporation under reduced pressure. The crude dipeptide is then subjected to low-pressure column chromatography on silica gel to afford N-t-butoxycarbonyl-L-tryptophyl-L-methionine benzyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04092304 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-a64ffbc761fa40b7bf66da369a1f19f6 |
| Source note | uspto-grants-1978_05 |