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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 372777Generated: October 30, 2026

Hydrochloric Acid → HCID 70620434, compound

https://huagongshe.com/reaction/372777

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 54048888HCID 54048888—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 70620434HCID 70620434—

Reaction Steps

The N-t-butoxycarbonyl-L-tyrosylglycylglycyl-L-tryptophyl-L-methionine is dissolved in 100 parts dioxane and stirred with a ten-fold excess of 2 N hydrochloric acid at room temperature for 15 minutes. The solvent is then removed under reduced pressure and the residue is triturated with ethyl ether. The resulting solid is precipitated from the mixture of methanol and ether to afford L-tyrosylglycylglycyl-L-tryptophyl-L-methionine hydrochloride. This compound is represented by the following formula

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04092304
Source datasetuspto-grants-1978_05
ORD IDord-3bae411051c84cdba4204a9f6b597017
Source noteuspto-grants-1978_05