HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetate → HCID 70619535, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetate | HCID 175 | — |
| Reactant | HCID 70620434 | HCID 70620434 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 70619535 | HCID 70619535 | — |
Reaction Steps
17.3 Parts L-tyrosylglycylglycyl-L-tryptophyl-L-methionine hydrochloride is dissolved in 250 parts by volume of 20% acetic acid and passed slowly through an IR-45 ion exchange column in the acetate form. The column is washed with 20% acetic acid until no more peptide is eluted. Fractions containing the product are combined and the solvent removed by stripping under reduced pressure at room temperature. The residual glass is dissolved in 75 parts water and lyophilized to give L-tyrosylglycylglycyl-L-tryptophyl-L-methionine acetic acid salt. This compound is represented by the following formula
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04092304 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-b6539617919848d1a54a7a3195315bce |
| Source note | uspto-grants-1978_05 |