HCID 53790063, compound → HCID 54546758, compound

HRID 372780Notes

Reaction equation

HRID 372780 reaction equation
ClC1C(O[C:9](=[O:26])[C@H:10]([CH2:19][CH:20]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]2)[NH:11][C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13])=C(Cl)C(Cl)=C(Cl)C=1Cl.[CH2:31]([O:38][C:39](=[O:67])[C@H:40]([CH2:63][CH2:64][S:65][CH3:66])[NH:41]C(=O)[C@H](CC1C2C(=CC=CC=2)NC=1)NC(OC(C)(C)C)=O)[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH2:31]([O:38][C:39](=[O:67])[C@H:40]([CH2:63][CH2:64][S:65][CH3:66])[NH:41][C:9](=[O:26])[C@H:10]([CH2:19][CH:20]1[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]1)[NH:11][C:12]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:13])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1

Participants

3

Reactant 2

HCID 53790063HCID 53790063, compoundHCID 53996203HCID 53996203, compound

Product 1

HCID 54546758HCID 54546758, compound

Procedure

When an equivalent quantity of N-t-butoxycarbonylhexahydro-L-phenylalanine pentachlorophenyl ester is substituted for the N-t-butoxycarbonyl-L-tryptophan 2,4,5-trichlorophenyl ester of Example 5 and the procedure detailed therein substantially repeated, there is obtained N-t-butoxycarbonylhexahydro-L-phenylalanyl-L-methionine benzyl ester.

Sources & evidence

ORD record
ord-a4cdece1464d4e5198662c30f72ca3cc
Source dataset
uspto-grants-1978_05
Patent number
US04092304

Reaction notes

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