HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hexane → 1,5-Naphthyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hexane | HCID 8058 | — |
| Edukt | 3-Aminopyridine | HCID 10009 | — |
| Edukt | 1,5-Naphthyridine | HCID 136070 | — |
| Katalysator | Adams' catalyst | HCID 345198 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 1,5-Naphthyridine | HCID 136070 | — |
| Produkt | 1,2,3,4-Tetrahydro-1,5-naphthyridine | HCID 6917495 | — |
Reaktionsschritte
1,5-Naphthyridine was prepared from 3-aminopyridine according to the method described in J. Org. Chem., 1963, 1757 and was isolated as colourless needles from n-hexane m.p. 69° C (lit. 74°). 1,5-Naphthyridine (2.6 g.) was hydrogenated in 95% ethanol over PtO2 catalyst under atmospheric conditions to give 1,2,3,4-tetrahydro-1,5-naphthyridine as colourless needles (2.51 g.).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04092418 |
| Quelldatensatz | uspto-grants-1978_05 |
| ORD ID | ord-df3d0aeec4c8496095d7f9e632740537 |
| Quellennotiz | uspto-grants-1978_05 |