Formic Acid → HCID 20322200, compound

HRID 372891Notes

Reaction equation

HRID 372891 reaction equation
[C:1]([CH:4]([CH2:14][CH2:15][CH2:16][CH:17]([OH:23])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12])(=[O:3])[CH3:2].[CH:24](O)=[O:25]>>[C:1]([CH:4]([CH2:14][CH2:15][CH2:16][CH:17]([O:23][CH:24]=[O:25])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 284Formic AcidHCID 12042400Heptadecanoic acid, 8-acetyl-12-hydroxy-

Product 1

HCID 20322200HCID 20322200, compound

Procedure

A mixture of 8-acetyl-12-hydroxyheptadecanoic acid (8.2 g., 0.025 mole) and 97% formic acid (10 ml.) is heated at 60° for 24 hours. The mixture is cooled, dissolved in 100 ml. ether, washed with 3 portions of water and dried over sodium sulfate. Evaporation of the ether leaves the product 8-acetyl-12-formyloxyheptadecanoic acid as a slightly yellowish viscous oil.

Workup

  1. temperatureis heated at 60° for 24 hours
  2. temperatureThe mixture is cooled
  3. dissolutiondissolved in 100 ml
  4. washether, washed with 3 portions of water
  5. dry with materialdried over sodium sulfate
  6. customEvaporation of the ether

Sources & evidence

ORD record
ord-8def5a79f8824496af60c5b1d324416c
Source dataset
uspto-grants-1978_05
Patent number
US04092356

Reaction notes

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