HCID 20322202, compound → HCID 20322318, compound

Participants

Reaction Steps

A solution of 8-(3-hydroxypropionyl)-12-hydroxyheptadecanoic acid . 1/3 chloroformate (Example 8, Step G) (3.58 g., 0.01 mole) in chloroform (5 ml.) is applied to a silica gel column (100 g., E. Merck, Darmstadt, 0.05-0.2 mm.). The column is allowed to stand at 25° for 24 hours, then eluted with chloroform-methanol (98:2) to slowly elute the title compound as a pale yellow oil.

Provenance & Evidence