HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 8-Acetyl-12-oxoheptadecanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Heptadecanoic acid, 8-acetyl-12-hydroxy- | HCID 12042400 | — |
| Catalyst | chromium (VI) trioxide | HCID 10219390 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 8-Acetyl-12-oxoheptadecanoic acid | HCID 20322271 | — |
Reaction Steps
A solution of 8-acetyl-12-hydroxyheptadecanoic acid (9.85 g., 0.03 mole) in acetone (29 ml.) is cooled to 5°-10° and treated, dropwise, over 21/4 hours with a solution prepared from a mixture of chromium trioxide (2.57 g., 0.0257 mole) water (7.5 ml.) and concentrated sulfuric acid (2.1 ml.). Stirring is continued for an additional 30 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04092356 |
| Source dataset | uspto-grants-1978_05 |
| ORD ID | ord-62d28c9715ce4165964e0c9287dae71c |
| Source note | uspto-grants-1978_05 |