反应详情

Following the procedure of Example 5, a mixture of 5-(4-chlorobutyl)-3-phenyl-2-oxazolidinone (3.0 g, 0.01186 mol), 1(2methyoxyphenyl)-piperazine (2288g, 0.01186 mol), potassium carbonate (4.92 g, 0.0356 mol) and potassium iodide (1 g) in 1-butanol (75 ml) gave an oil (4.7 g, 87% yield), which was crystallized from isopropanol/isopropyl ether. Drying of the resulting solid under high vacuum gave 0.98 g, mp 153°-155° C.