反应详情

Following the procedure of Example 5, a mixture of 5-(3-chloropropyl)-3-phenyl-2-oxazolidinone (4.5 g, 0.0188 mol), 1-(2-pyridinyl)piperazine (3.07 g, 0.0188 mol), potassium carbonate (7.81 g, 0.0565 mol), and potassium iodide (1.0 g) in n-butanol (200 mL) gave a solid which was recrystallized from isopropanol/isopropyl ether and dried under high vacuum to give 3.86 g (56% yield), mp 123°-125° C.

1. customgave a solid which
2. customwas recrystallized from isopropanol/isopropyl ether
3. customdried under high vacuum
4. customto give 3.86 g (56% yield), mp 123°-125° C.