反应详情

Following the procedure of Example 5, a mixture of 5-(3-chloropropyl)-3-phenyl-2-oxazolidinone (4.5 g, 0.0188 mol), 1-(2-pyrimidyl)piperazine dihydrochloride (4.47 g, 0.0188 mol), potassium carbonate (15.64 g, 0.113 mol), and potassium iodide (1.0 g) in n-butanol (200 mL) gave a solid which was recrystallized from isopropanol/isopropyl ether and dried under high vacuum to give 2.49 g (36% yield), mp 92°-98° C. and 118° C.

1. customgave a solid which
2. customwas recrystallized from isopropanol/isopropyl ether
3. customdried under high vacuum
4. customto give 2.49 g (36% yield), mp 92°-98° C. and 118° C.