反应详情

Following the procedure of Example 5, a mixture of 5-(3-chloropropyl)-3-phenyl-2-oxazolidinone (4.5 g, 0.0188 mol), 1-(2-methoxyphenyl)-piperazine (3.62 g, 0.0188 mol), potassium carbonate (7.81 g, 0.0565 mol), and potassium iodide (1.0 g) in n-butanol (200 mL) gave an oil. The oil was acidified with warm ethanolic hydrogen chloride, filtered warm, and cooled to room temperature. Diethyl ether was added and the resulting solid was collected by filtration and dried under high vacuum at 50° C. to give 4.65 g (53% yield), mp 203°-211° C.

1. customgave an oil
2. filtrationfiltered
3. temperaturewarm
4. additionDiethyl ether was added
5. filtrationthe resulting solid was collected by filtration
6. customdried under high vacuum at 50° C.
7. customto give 4.65 g (53% yield), mp 203°-211° C.